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Clinical trials that are designed to help inform practice in the real world are known as pragmatic trials. They are typically focused on practical aspects of the study design, including the recruitment process and consent, adherence, and the use of commonly available equipment.

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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which utilized different investigators and participants from different geographical regions. This type of heterogeneity is essential for practical trials to be valid, and 무료 프라그마틱 무료체험 메타 (pop over to this site) it also helps to reduce the chance of bias in the results. However, too much heterogeneity can result in problems with the trial design.

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Pragmatic trials are designed to replicate real-world situations and have the highest external validity. Usually, they are ordered by policymakers and practitioners to help inform their decisions. They can be used to determine the cause-effect relationship of an intervention and its results. However, 프라그마틱 정품확인 they shouldn't be used as a substitute for explanation studies.

The concept of pragmatism is controversial and there are concerns regarding whether pragmatic trials could be used to replace explanation tests or if they are a complement to them. Schwartz and Lellouch1 suggested the distinction between explanatory trials, which prove the clinical or physiological hypothesis, and pragmatic trials, which inform policy and practice decisions. They also suggested an approach to pragmatic trials, which they called PRECIS.2 This tool sought to define the elements of a pragmatic study that include the recruitment process, 프라그마틱 슬롯체험 the design and implementation of the intervention, as well as the follow-up.

There is an encouraging trend in the number of pragmatic trials that have been published. A recent Medline query that used the words naturalistic and pragmatic, restricted to randomised controlled trials (RCTs) returned 34 articles. These are highlighted in red on Figure 2. This is a sign that the health science community is becoming increasingly sensitized to the issue of pragmatics. It is important to keep in mind, however, that the majority of these studies were conducted in primary care settings.